Renowned virologist and member of the prestigious National Academy of Science, Peter Duesberg has argued that AIDS is not caused by HIV, but is the result of recreational and anti-HIV drugs. In this PBL case, students read Duesberg's 1999 article in Science magazine titled "HIV is Not the Cause of AIDS" as well as a response to it titled "HIV Causes AIDS" by medical researchers Dr. William A. Blattner and colleagues. Students work in groups to identify the issues as well as any terms or concepts they don't understand, then research these out of class to pool their information as they learn about AIDS and HIV.

This three-part progressive disclosure case is designed to introduce pharmacy students to the pharmacist's role in long-term care (LTC) facility consulting pharmacy practice and acquaint them with the essential, basic resources for conducting a drug regimen review.

This PBL case on Intelligent Design was written for freshman biology majors at a Christian liberal arts college. Students read about the claims and actions of proponents of Intelligent Design as they work for its inclusion in the high school science curriculum. In the process, students learn about the nature of science and the importance of evolution in the field of biology. More advanced students are given the task of critically evaluating one specific (and much cited) claim made by Intelligent Design supporters that the irreducible complexity of the bacterial flagellum suggests it cannot be the product of evolution.