In this exercise, students will explore the structures of the macromolecular building blocks using StarBiochem.
In this exercise, students will explore the structure of a DNA repair protein found in most species, including bacteria. DNA repair proteins move along DNA strands, checking for mistakes or damage. DNA glycosylases, a specific type of DNA repair protein, recognize DNA bases that have been chemically altered and remove them, leaving a site in the DNA without a base. Other proteins then come along to fill in the missing DNA base.
In this exercise, students will explore how a single alteration in the amino acid sequence of the hemoglobin protein results in sickle cell anemia.
In this exercise, students will use StarBiochem to explore the structure of the enzyme phenylalanine hydroxylase (PAH) and determine the relationship between the structure of a mutated form of PAH and the function of this mutated protein in patients with PKU.