This lesson uses the fundamentals of protein synthesis as a context for investigating the closest living relative to Tyrannosaurus rex and evaluating whether or not paleontologist and dinosaur expert, Jack Horner, will be able to "create" live dinosaurs in the lab. The first objective is for students to be able to access and properly utilize the NIH's protein sequence database to perform a BLAST, using biochemical evidence to determine T rex's closest living relative. The second objective is for students to be able to explain and evaluate Jack Horner's plans for creating live dinosaurs in the lab.

Giving us credit when you use our content and technology is not just important for legal reasons. When you provide attribution to CK-12 Foundation, you support the ability of our non-profit organization to make great educational experiences available to students around the world.Our Creative Commons License welcomes you to use our content and technology when you give us attribution. If you have any questions about our policies, contact us at support@ck12.org

Students interpret molecular diagrams and build physical models of eukaryotic gene regulation in this hands-on activity.

This advanced lesson describes the role of mutations in the birth and death of genes. Questions challenge students to synthesize information and apply what they learn regarding how genes are gained and lost through evolutionary time. Background information, examples, video clips, and animations are also included.

Students transcribe and translate portions of the wild-type and mutant rock pocket mouse genes and compare sequences to identify the locations and types of mutations responsible for the coat color variation.

In this lesson, students will explore how variations in DNA sequences produce varying phenotypes. Students will complete transcription and translation of DNA and RNA and then determine phenotypes produced based on amino acid sequences while completing hands on activity. During this lesson, students will create a factious organism by rolling a dice to determine which DNA sequence it will receive. Students will then perform transcription and translation. Finally, students will determine the phenotype of the organisms by comparing its amino acid sequence to a key that will be provided. Lastly, students will create a picture of the fictitious organism.

Students analyze amino acid data and draw conclusions about the evolution of coat color phenotypes in different rock pocket mouse populations.

In this exercise, students will use StarBiochem to explore the structure of the enzyme phenylalanine hydroxylase (PAH) and determine the relationship between the structure of a mutated form of PAH and the function of this mutated protein in patients with PKU.

In this activity, students will assume the functions of various cell organelles and RNA to simulate cell processes and protein synthesis. They will compete against other classes to determine which "cell" has the lowest time for creating six proteins.

This resource accompanies the activity "Protein Power Game". Students cut apart small cards to use to complete the chart that outlines the functions of each organelle as well as memory clues that can be used to help them remember the functions. It is not required for the game, but it serves as a useful pre-game review of the functions of cell organelles.

This resource contains the masters to use for the organelle necklaces for the activity "Protein Power Game".

This Power Point presentation accompanies the activity "Protein Power Game" and is used to introduce the game and to review the functions of cell organelles and the process of protein synthesis.

This resource shows the protein models students need to make during the activity "Protein Power Game".

This worksheet accompanies the activity "Protein Power Game" and includes background information and review questions.

Protein SynthesisGiving us credit when you use our content and technology is not just important for legal reasons. When you provide attribution to CK-12 Foundation, you support the ability of our non-profit organization to make great educational experiences available to students around the world.Our Creative Commons License welcomes you to use our content and technology when you give us attribution. If you have any questions about our policies, contact us at support@ck12.org

The student will use knowledge they have learned through direct instruction to illustrate the creation and copying of the molecular structure of DNA and RNA. They will accomplish this by creating a comic strip and/or storyboard that graphically describes transcription and translation.

This interactive animation shows the transcription process of RNA within the plant cell nucleus, followed by the movement of the single stranded RNA out of the nucleus where it is translated into proteins.

This brief video lesson discusses X chromosome inactivation and how this can affect the expression of certain genes. Discussion/assessment questions and suggested supplemental resources are also included.

Students investigate sickle cell anemia to teach the principles of inheritance, genetic diagnostics, and bioethics.